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10 Ways Digital Twins Are Personalizing Patient Care in 2025

Mayank Pratap Singh
Founder & CEO of Engineerbabu

What if your doctor could test a treatment on “you” without ever touching you? That’s not science fiction anymore. It’s happening now, thanks to digital twins.

A digital twin is a virtual replica of a real person. It uses your medical history, test results, wearables, even your DNA to build a model of your body. Doctors and researchers then use that model to see how you might respond to treatments before they try anything on the real you.

This tech isn’t just on the horizon—it’s already changing how care is delivered. The healthcare digital twin market hit $902 million in 2024, and it’s expected to grow almost 26% every year through 2030. That’s a big signal that hospitals, clinics, and healthtech startups are all-in on using this to deliver care that’s truly personalized.

In this post, we’ll break down 10 powerful ways digital twins are transforming patient care in 2025. From treatment plans made just for you, to early warnings that could save your life—you’ll see how this tech is making care smarter, faster, and a whole lot more personal.

How Digital Twins are Personalizing Patient care

Personalized Treatment Planning

Picture this—you’re diagnosed with a condition, and before your doctor gives you any medication or therapy, they run simulations on a virtual version of you. That’s exactly what digital twins are doing for personalized care.

Instead of relying on general guidelines, doctors can now test different treatment options on a patient’s digital twin. This helps them figure out what’s most likely to work for them based on their body, their genetics, their health history—everything.

A great example? The Olivia Newton-John Cancer Research Institute is teaming up with Hewlett Packard Enterprise to build digital models of tumors. These models let researchers simulate how different cancer drugs will interact with a specific patient’s tumor so they can find the best match faster—and skip the trial-and-error phase most cancer patients go through.

For healthcare providers, this means fewer adverse effects, more successful treatments, and way more confidence in clinical decisions. And for patients, it means feeling like your care was made just for you—because it was.

Real-Time Health Monitoring and Predictive Analytics

Digital twins can create virtual models of patients and continuously update them with real-time data from wearable devices and sensors. This allows healthcare providers to monitor your health 24/7. This constant stream of information allows them to detect subtle changes that might indicate the onset of a condition, enabling early intervention.​

Similarly, the NHS in England is trialing an AI tool called Aire to analyze electrocardiogram (ECG) results for predicting the risk of fatal heart disease. This tool can identify structural heart issues that may be imperceptible to doctors, suggesting further monitoring or treatment as needed. 

These advancements mean that healthcare is shifting from a reactive to a proactive approach. Instead of waiting for symptoms to appear, doctors can now anticipate and address potential health issues before they escalate, leading to better patient outcomes and more efficient healthcare delivery.​

Personalized Drug Response and Testing

Not everyone reacts to medications the same way. Two patients might take the same drug, but only one sees results—or worse, one gets side effects the other doesn’t. This is where digital twins are making a serious difference.

By building a virtual model of a person’s body and simulating how it processes medication, researchers can predict how a specific drug might affect a specific patient. That means fewer side effects, better dosing, and better outcomes overall.

A biotech company called Unlearn.AI is already working with pharmaceutical firms to create “digital twin control groups” for clinical trials. These digital models are trained on real patient data, and they help predict how people with certain traits might respond to a drug—without exposing them to it in real life. 

This helps speed up the development of new treatments while keeping actual patients safer during trials.

And it’s not just in the lab. Health systems can use this same idea to figure out which medications are most likely to work for someone, especially in complex cases like cancer or autoimmune disorders where treatment can be hit or miss.

Tailored Rehabilitation Programs

Recovering from an injury or surgery isn’t a one-size-fits-all process. Each person’s body responds differently to rehabilitation, and digital twins can help draft better post care programs. 

A therapist can create a virtual model of the patient’s body. Then, they can design rehab programs that are specifically tailored to your unique needs, ensuring a more effective and efficient recovery. 

For example, Sword Health has developed an AI-powered digital therapy platform that provides personalized physical therapy sessions. Patients use wearable sensors that feed data into their digital twin, allowing therapists to monitor progress in real-time and adjust exercises accordingly. 

This approach has been shown to improve patient outcomes and engagement compared to traditional methods. ​

Individualized Surgical Planning

Surgery is already high-stakes, but planning it around a patient’s specific anatomy? That’s where digital twins are changing everything.

Surgeons are now using digital replicas of a patient’s organs or systems to plan procedures down to the smallest detail. These models are built from scans like MRIs and CTs, combined with personal health data, so they reflect the patient’s real structure—not just a textbook version of it.

Take Dassault Systemes’ “Living Heart Project,” for example. It’s helping doctors simulate how a specific patient’s heart will react during surgery or when using a medical device. Instead of relying on general assumptions, surgeons can test different approaches virtually—minimizing risk when it’s time for the actual operation.

For patients, this kind of planning can reduce complications, shorten surgery time, and boost recovery. And for healthcare providers, it builds a whole new level of precision into how surgeries are prepared—and performed.

Personalized Chronic Disease Management

Living with a chronic illness like diabetes or heart disease can feel overwhelming. Managing medications, monitoring symptoms, and making lifestyle changes are all part of the daily routine. But what if technology could make this process more tailored and less burdensome?

Digital twins use real-time data to mirror an individual’s health status. These digital replicas enable healthcare providers to predict potential health events and adjust treatment plans proactively.​

For instance, a study involving over 1,800 patients with type 2 diabetes demonstrated that digital twins could provide personalized recommendations based on real-time data, leading to improved outcomes such as lower hemoglobin A1c levels and reduced medication needs. 

Similarly, Twin Health has developed a “Whole Body Digital Twin” that creates a virtual model of a patient’s metabolism using data from Bluetooth-connected sensors. This technology offers personalized health advice, considering factors like a woman’s menstrual cycle, which can affect various health aspects. ​

Genetic and Lifestyle Integration for Holistic Care

Health isn’t just about your symptoms—it’s also about your genes, your habits, your environment, and how all of those interact. That’s why digital twins that combine genetic data with lifestyle information are becoming such a powerful tool for personalized care.

Let’s say a patient has a family history of heart disease and follows a high-stress lifestyle. A digital twin can merge that genetic risk with real-world data from fitness trackers, diet logs, and even sleep monitors. The result? A much clearer picture of the patient’s actual risk—and a personalized plan to manage it.

In fact, researchers at the Icahn School of Medicine at Mount Sinai are already using this kind of data integration to predict disease risk and tailor prevention strategies. They combine genetic info with lifestyle factors to create “digital patient avatars,” helping doctors intervene before symptoms show up.

This level of insight isn’t just helpful—it’s lifesaving. Doctors can recommend specific lifestyle changes, spot red flags earlier, and design prevention plans that actually fit how someone lives.

Patient Empowerment Through Personalized Health Insights

When patients understand what’s going on in their bodies, they’re more likely to stay engaged and stick with their care. But let’s be honest—most people zone out halfway through a medical explanation. 

But with digital twins, patients don’t have to read charts or try to decipher medical jargon. Instead, patients can actually see what’s happening inside their own virtual body. Imagine being able to view how your blood pressure reacts to stress or how skipping sleep might raise your blood sugar. It’s a game-changer.

For someone with diabetes, for example, they can instantly see how different foods, workouts, or even stress affect their glucose levels. That kind of feedback makes a huge difference when it comes to motivation and behavior change.

Smarter Use of Hospital Resources

Hospitals deal with a lot of moving parts—beds, staff, machines, meds—you name it. One miscalculation, and you’ve got delays, wasted time, or worse, patients not getting what they need when they need it. Digital twins are helping fix that.

By using virtual models of patients and even entire hospital systems, healthcare providers can predict what resources will be needed, and when. Think of it like a real-time dashboard for patient flow, treatment timelines, and resource use.

For example, the University of Toronto used digital twin tech to model how patients move through their hospital system. With it, they could test different scheduling strategies, figure out where bottlenecks were happening, and improve patient flow—all without disrupting real patients.

This kind of predictive modeling helps hospitals stay ahead. If a patient’s digital twin shows they might need an ICU bed or a specific drug in the next few days, the system can plan for that. 

Bottom line? Care becomes smoother, wait times shrink, and resources don’t go to waste. 

More Personalized Remote and Telehealth Care

Telehealth used to mean a quick video call and maybe a prescription refill. But with digital twins in the mix, remote care is getting a serious upgrade.

Now, doctors can access a patient’s digital twin—complete with real-time data from wearables, past health records, and ongoing symptoms—and use that to guide remote consultations. It’s not just chatting on Zoom anymore; it’s informed, personalized care from a distance.

Companies like Biofourmis are already doing this. Their platform uses continuous data from wearables to create dynamic digital models of patients with conditions like heart failure. Doctors can track changes, tweak medications, or schedule check-ins before symptoms get worse.

This is a big deal for people who live in rural areas, can’t travel easily, or just prefer staying home. It also makes follow-up care way more proactive. Instead of waiting for someone to call and say, “Hey, I don’t feel right,” doctors can reach out first—because the data already saw it coming.

How to Build a Digital Twin in Healthcare

Alright, so digital twins sound impressive—but how do you actually build one?

It starts with data. You need health records, lab results, sensor inputs (like wearables or IoT devices), and sometimes even genetic info. That data feeds into a system—usually built using AI and machine learning—that can create a dynamic, virtual model of the patient.

Next comes integration. This is where many providers hit a wall. Systems need to talk to each other, real-time updates have to work seamlessly, and privacy has to be airtight. That’s a pretty heavy lift, especially for hospitals or startups juggling limited dev teams.

This is where app development companies come in. Experienced companies that actually get the complexity of healthcare systems can integrate wearables with EMRs or build the AI backbone for a predictive model.

Once built, the digital twin needs continuous updates. You want it to learn and adapt constantly—so it’s not just a snapshot, it’s a living, breathing model (well, virtual breathing).

In short: building a digital twin isn’t plug-and-play—but with the right data, the right tech stack, and the right team, it’s totally doable. And the payoff? Massive.

Final Thoughts

The real value of digital twins in healthcare isn’t the tech itself—it’s what that tech allows us to do differently. It helps doctors stop guessing. It helps patients stop second-guessing. And it brings a level of precision to care that just wasn’t possible a few years ago.

Digital Twins are not replacing human expertise. They’re just giving that expertise sharper tools, better data, and a clearer view of each patient. We’re seeing the early signs already: fewer side effects, faster recoveries, smarter interventions.

If you’re in healthcare and still watching from the sidelines, now’s the time to move. The future of care is personal—and it’s being built, quite literally, one twin at a time.

The key takeaway? Personalization in patient care isn’t a buzzword anymore. It’s real, measurable, and powered by tech-like digital twins. And as this space keeps growing, being able to implement or innovate with digital twin technology might be what sets your care—or your product—apart.

FAQs

 What exactly is a digital twin in healthcare?
A digital twin is a virtual replica of a real patient that updates in real-time using medical records, sensors, and other data. Doctors use it to test treatments, predict outcomes, and personalize care.

How accurate are digital twins?
When fed with enough quality data, digital twins can be highly accurate. Their predictive power depends on how personalized the inputs are—things like genetics, lifestyle, and real-time biometrics all help improve results.

Can digital twins help with early diagnosis?
Yes. By continuously monitoring changes and comparing them to a patient’s baseline, digital twins can flag early warning signs of disease—sometimes before symptoms even show up.

Are digital twins safe for patient privacy?
They can be, as long as they follow strict data protection standards like HIPAA or GDPR. Encryption, access control, and anonymization are key to keeping personal health info secure.

How do I build a digital twin for my healthcare product or service?
You’ll need access to health data, the right tech stack (AI, cloud, IoT), and a team that understands both healthcare and software development. If you’re looking to build fast without cutting corners, Engineerbabu is an experienced IT services provider that specializes in digital health solutions.

Author

  • Mayank Pratab Singh - Co-founder & CEO of Supersourcing

    Founder of EngineerBabu and one of the top voices in the startup ecosystem. With over 13 years of experience, he has helped 70+ startups scale globally—30+ of which are funded, and several have made it to Y Combinator. His expertise spans product development, engineering, marketing, and strategic hiring. A trusted advisor to founders, Mayank bridges the gap between visionary ideas and world-class tech execution.

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